A thin polymer strip placed under the tongue that hydrates and disintegrates in ~10–60 s, delivering an accurate unit dose with discreet, water-free use. Depending on the active and design, it can enable rapid onset via mucosal absorption.
Where It Fits (Use Cases)
- Energy & focus: caffeine/theanine micro-doses for commuters.
- Sleep support: melatonin at bedside, pill-free.
- Oral care & fresh breath: menthol/xylitol concepts (market-dependent).
- Electrolytes & vitamins: convenient daily adherence.
- Pediatric/geriatric: easier than tablets or capsules.
Compliance note: Drug/OTC/nicotine formulations require jurisdiction-specific approvals; examples describe the format, not claims.
Formulation Snapshot
- Matrix: Pullulan / HPMC / PVA (single or blends).
- Plasticizer: Glycerin or PEG-400 for flexibility.
- Taste system: Sucralose/acesulfame-K + citric/malic acid + natural flavors.
- Targets: thickness 40–100 µm; disintegration ≤60 s; content uniformity RSD ≤3–5%.
Manufacturing (High Level)
- Polymer solution → add plasticizer/flavors → incorporate active → de-aerate.
- Cast to controlled coat weight → zoned drying to moisture window.
- Condition → slit → die-cut to unit size (e.g., 25×30 mm).
- Pack: individual aluminum high-barrier four-side-seal sachets (low WVTR/OTR).
Packaging & Stability