Looking to scale from lab strips to commercial runs? oral thin strip machinery turns slurry into consistent, pouch-ready films with tight control over thickness, dose, and moisture.

What it does (end-to-end)

Coat (slot-die/comma) → multi-zone dry → in-line gauge (thickness/GSM) → slit/die-cut → sachet/blister pack.

Why it matters

• Uniform dose: Closed-loop thickness control, CV ≤ ±2–3% with proper upstream QC.
• Throughput: Pilot 5–20 m/min; commercial 20–60+ m/min on wider webs.
• Stability: Low-humidity drying + high-barrier pack lowers WVTR/OTR exposure.
• Flexibility: HPMC/pullulan/PVA matrices, single/multi-layer, flavor lanes.

Selection checklist (fast)

• Coater: Slot-die with precision pump & edge guides; quick shim change.
• Dryer: 3–7 zones, independent T/RH control, solvent-safe if needed.
• Metrology: Beta/IR gauge + vision; SPC dashboard + recipe library.
• Conversion: Rotary die-cut with waste matrix removal; auto pick-and-place.
• Packaging: Four-side-seal sachet (easy-tear / laser notch), inline print/inspect.
• Compliance: cGMP design, 21 CFR Part 11 data, IQ/OQ/PQ support.

Scale path

Bench coater → pilot line (process window map) → commercial line (wider web, higher speed) with the same recipes to reduce tech transfer risk.

CTA: Start with a pilot trial to lock disintegration (≤10 s) and mouthfeel, then spec the production line around your validated GSM and packaging.

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